Dr. Yaohua Zhang, a professor at Peking University Third Hospital, holds the position of Principal Investigator (PI) for the National Key Laboratory of Vascular Homeostasis and Remodeling. Before this, he conducted postdoctoral research at the University of Texas Health Science Center in Houston and the renowned MD Anderson Cancer Center in the United States. Acknowledged for his exceptional contributions, Dr. Zhang was honored with the 2022 Beijing Overseas High-level Talents Youth Program and received funding from the Science Fund Program for Excellent Young Scientists (Overseas) in the same year. His research endeavors primarily delve into the mechanisms behind post-translational protein modifications in cardiovascular diseases, leveraging multi-omics technology. His ultimate aim is to establish biomarkers for disease scoring and stratification, thereby enhancing the accuracy of diagnosis and precision in intervention strategies. In the past five years, he has led or contributed significantly to numerous highly influential academic publications in esteemed international journals such as Science, Nature Cell Biology, Circulation, and Science Translational Medicine, collectively achieving a cumulative impact factor surpassing 200.

Education

PhD, Biochemistry and Molecular Biology, Peking Union Medical College, 2013-2016

MS, Biochemistry and Molecular Biology, Shanxi University, 2009-2012

Bachelor of Management, Information Management and Information Systems, Shanxi Agricultural University, 2007-2009

Bachelor of Science, Biological Sciences, Shanxi Agricultural University, 2005-2009

Research Experiences

2023/10 to Current Associate professor, Peking University Third Hospital

2022/01-2023/10 Professor, Beijing Institute of Brain Diseases

2017/12 -2021/12 Postdoctoral research fellow, MD Anderson Cancer Center

2017/05 -2017/12 Postdoctoral research fellow, The University of Texas Health Science Center at Houston

2012/08-2013/06 Research Assistant, National Center for Cardiovascular Diseases

Research interests

o Research on the pathogenesis and diagnosis of heart failure based on protein post-translational modification

o Development of biomarkers and molecular imaging probes for stratification of coronary heart disease diagnosis

o Research on new protein post-translational modifications and development of new intervention methods for cardiovascular disease Drugs, gut microbiome, and cardiometabolic disease (CMD)